MS9ZE

Prompt

1.13.11.17

Oxidoreductases. Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. With incorporation of two atoms of oxygen. indole 2,3-dioxygenase.

AI Generated Sequence

356 AAs

MERPVPSLADYDVSPEHGFLPDRPPLERLPDPYYAPWEAIAANLPQLILSRRLRGVIDRMPVLSTVGLHDHAEWRRAHSVLSFMAHGYIWGGDAPAERLPPRIAVPLLEVSEHLGLPPVATYAAVCLTNWKVIDPDEPIDLENLATLTTFTGSRDESWFYLVSVAIEARAGPAIPLVMTALDAARRDDRAAVTECLRTFARCIADIGTLLERMHEHCDPHVFYHRIRPFLAGSKNMAEAGLPNGVVYEDGTGEEPYRQYSGGSNAQSSLIQFFDILLGVEHRPTGEKRASESAAPAAPAPAPAPAPAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	84.3
NLMSIM	95.0
AACOMP	82.9
Seqdif (SeqID)	23.8 (KAF5008017.1)
Structdif (F-Target)	21.7 (8abx A)

ProtNLM

Name	Score
Indoleamine 2,3-dioxygenase	0.379
Indoleamine 2,3-dioxygenase subfamily	0.228
Indoleamine 2,3-dioxygenase family protein	0.052
Indoleamine 2,3-dioxygenase 2	0.032
Indoleamine 2,3-dioxygenase 1	0.028
Indoleamine 2,3-dioxygenase alpha type	0.025