MS7GY

Prompt

1.1.1.157

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. 3-hydroxybutyryl-CoA dehydrogenase.

AI Generated Sequence

291 AAs

MSIQKVGVIGAGQMGNGIAQVSALAGYDVVMNDISADALEKGIATIGKSLDRQVSKGKITAEQKAAALARIKGSTTLADLADCDLVIEAATENEELKLKIFKQLCPHLKPETILASNTSSISITRLASVTDRPERFIGMHFMNPVPVMQLVELIRGLATSDETYDACKAVAEKLGKTPVTVENFPGFVVNRILVPMINEAIYTLYEGVATVESIDTAMKLGANHPIGPLALADFIGLDTCLAIMNVLHEGFGDSKYRPCPLLKEYVAAGWLGRKTGRGFYDYRGETPVPTR

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	96.9
NLMSIM	90.0
AACOMP	95.3
Seqdif (SeqID)	25.8 (WP_194097909.1)
Structdif (F-Target)	1.8 (4r1n A)

ProtNLM

Name	Score
3-hydroxybutyryl-CoA dehydrogenase	0.572
1.1.1.157	0.383
3-hydroxyacyl-CoA dehydrogenase	0.032
1.1.1.35	0.003
Beta-hydroxybutyryl-CoA dehydrogenase	0.001
3-hydroxybutyryl-CoA dehydrogenase (Beta-hydroxybutyryl-CoA dehydrogenase) (BHBD)	0.001