MS4KU

Prompt

1.14.19.11

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water. acyl-[acyl-carrier-protein] 4-desaturase.

AI Generated Sequence

297 AAs
MPPQKVELIKSLEPWVEENLLTHLKPVEKCWMPQDFLPDSASFNGFLEQVKEWRARSAELPDDYFVCLVGNMITEDALPTYHTFLNDFDGVRDSTWATWTRAWTAEENRHGDLLNKYLYLSGRVDMRQIEKTQIHYIKSGMDPNTENNPYLGFIYTSFQERATFISHGNTARLAKALGDPVLAQLCGQIATDEKRHETAYTNFIKKLFEIDPDGTLLAIADMIRKKITMPAHLMDYGDKNLFDFSQVAQERNIYTAKDYANILEFLVGWKVDENLTGLSGEGRKAQDYLCGLPARIR

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT84.0
NLMSIM70.0
AACOMP94.1
Seqdif (SeqID)24.5 (RZC24878.1)
Structdif (F-Target)6.0 (4v0j A)

ProtNLM

NameScore
Acyl-[acyl-carrier-protein] desaturase0.373
1.14.19.-0.267
1.14.19.20.125
Acyl-ACP desaturase0.060
Stearoyl-[acyl-carrier-protein] 9-desaturase0.028
1.14.19.110.017
Designed by MP, using an AMD MI250 GPU