MRN9G

Prompt

1.5.98.2

Oxidoreductases. Acting on the CH-NH group of donors. With other, known, acceptors. 5,10-methylenetetrahydromethanopterin reductase.

AI Generated Sequence

289 AAs

MKIGIEIPVGDPTVNVEEAAKYAEELGFENVWISDHYNNRGVYSRPMTLTAALAAQTNRIGVGTSVVNSHRSPAITAASISTLDELSGGRAILGLGPGDGFTEFTEMGWDWEKRYPRLTKEAIEVLRVLYSGETVTFDGELYKFDNLGLKYIKPGKPVPIYMGAQGPAMLKVAGEVADGILINAGNPDVFEKAKEIKKLGAEAGITHEEFDVAYCVACISDSDPEAAKAAKEIVAAIVAVGGVFAGGAPDVPEQIKGGIDAIKEGVKIIPGVKIIEEFKKALGEIAKKH

Ligand/Cofactor

5-methyltetrahydromethanopterin

CC1C(N(C2=C(N1)N=C(NC2=O)N)C)C(C)NC3=CC=C(C=C3)CC(C(C(COC4C(C(C(O4)COP(=O)(O)OC(CCC(=O)O)C(=O)O)O)O)O)O)O

Validation Metrics

PLDDT	70.8
NLMSIM	75.0
AACOMP	90.2
Seqdif (SeqID)	47.5 (HII03026.1)
Structdif (F-Target)	16.9 (5lxe B)

ProtNLM

Name	Score
5,10-methylenetetrahydromethanopterin reductase	0.358
1.5.98.2	0.204
Coenzyme F420-dependent N(5),N(10)-methylenetetrahydromethanopterin reductase	0.189
Methylene-H(4)MPT reductase	0.082
LLM class flavin-dependent oxidoreductase	0.038
Bac_luciferase domain-containing protein	0.010