MRKOV

Prompt

1.14.13.35

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. With NADH or NADPH as one donor, and incorporation of one atom of oxygen. anthranilate 3-monooxygenase (deaminating).

AI Generated Sequence

290 AAs
MSKKVVVVGAGLAGGLALLLAKKLGRDVDFEVLSRDPNYHTFPKPLSSLAAGSVEARAISEPIREIFRKHGCEFMRGEAVHIDKETKLIQAQLKGKFSIAYDYLVIALGSQNTFGHTPGVENHFFLKEIHDAQAIRNTIMQNFEEAYPLTEEEREKLLDFAIVAGGATGVEFAGELYDFITDVLYKYFPEIDLNAIKIHLIDARSHILAPFPERMIAYALNQFKDRVEIWLTNGMVEKVEEGTLKTKEGEEIPFGTMVWATVGIQNPFVKDFAELGLTRGVKLEVDPYHQ

Ligand/Cofactor

NADH

C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O

Validation Metrics

PLDDT88.5
NLMSIM85.0
AACOMP93.4
Seqdif (SeqID)57.8 (XP_047307990.1)
Structdif (F-Target)10.2 (5kmq C)

ProtNLM

NameScore
Pyr_redox_2 domain-containing protein0.884
Pyridine nucleotide-disulfide oxidoreductase0.022
NAD(P)/FAD-dependent oxidoreductase0.022
FAD-dependent oxidoreductase0.021
NADH dehydrogenase0.010
FAD-dependent pyridine nucleotide-disulfide oxidoreductase0.006
Designed by MP, using an AMD MI250 GPU