MRI07

Prompt

1.1.1.308

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. sulfopropanediol 3-dehydrogenase.

AI Generated Sequence

500 AAs

MTEVYLKKALTRETADNDKVTKIVQGILDDIEKRGDKAVRDYALKFDKYDGSGVRLSEKEIEEAMELVPKDVKEDIEFAQKQVRRFAEAQKKSMTMDVEVLPGVRVGQKAIPVSSAGCYVPGGRYSHIASAAMSVATAKVAGCKHIIACSPPRPGGVIAPAIVYAQHICGADRILAMGGVQAVAAMTFGLFTLGKANILVGPGNQFVAEAKRILFGRIGIDMFAGPTESMILADETADPDIVATDLVGQAEHGYNSPVWLVTDSKKLAEEVMKEVPRLLEELPETNRNTAKAAWEDYGEVIVCDTLEEMEVCSDEYAPEHLHVQTEDFDFWLDRMTCYGSLFLGEETTVSYGDKVSGTNHVLPTKKAARYTGGLSVGKFMKTVTWQRCTEEGSKLIGEATSRLSRLEGMEGHARSCDIRLDKYGPFTEVPYVEEEIPFLTQETIPFLEELKKELEKLKEELEKLKEEYEKLLKEYGFEPHANRAAERIKNAWGKKNKKNN

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	90.8
NLMSIM	90.0
AACOMP	92.7
Seqdif (SeqID)	30.8 (WP_091844513.1)
Structdif (F-Target)	8.0 (6an0 2)

ProtNLM

Name	Score
Sulfopropanediol 3-dehydrogenase	0.238
1.1.1.308	0.203
Histidinol dehydrogenase	0.190
1.1.1.23	0.118
2,3-dihydroxypropane-1-sulfonate 3-dehydrogenase (sulfolactate forming)	0.081
DHPS 3-dehydrogenase (sulfolactate forming)	0.073