MRHQ4

Prompt

6.2.1.26

Ligases. Forming carbon-sulfur bonds. Acid--thiol ligases. o-succinylbenzoate--CoA ligase.

AI Generated Sequence

499 AAs

MTLPELLWRRAARTPDRTALVDGDGRTTYGELHARVDRLAAALRAAGVGRGDRVAVLLGNSPEMVVALHGALAAGAVVVPLNTRLPAAELAYQLDDADCAAVVTDAAFAPGVDAVPAAGVPVRLVALDGPGPGPVSFADLAAAPPPPPPPPPPDDTALITYTSGTTGRPKGVVLTHGNLLNAMAGVQAWLGLRPGDRLWLAVPLFHVGGLSLVLARLVFGATVVLLPRFDPARFLDAIERHRVTHLAGVPQMLARLLADPALGRDYPASLRQLVLGGAPLPPALLERARERGLPVRQAYGMTETASQVVTLAPGDLARRPGSVGRPLFPHEVRIVDEDGREVPPGEVGELLVRGPNVMAGYWNRPEATREAFTPDGWLRTGDLGYLDEDGFLRLVGRLKEMIISGGENVYPSEVEAVLAAHPGVAEAAVVGVPDERWGEQPVAFVVLRPGAELDEAELRAHCRGRLAPYKVPRRVEFFDELPRNASGKVLRKELREALG

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	93.1
NLMSIM	80.0
AACOMP	87.4
Seqdif (SeqID)	48.9 (HLT59303.1)
Structdif (F-Target)	4.7 (5bur A)

ProtNLM

Name	Score
O-succinylbenzoyl-CoA synthetase	0.359
6.2.1.26	0.325
2-succinylbenzoate--CoA ligase	0.078
OSB-CoA synthetase	0.057
6.2.1.3	0.032
O-succinylbenzoate--CoA ligase	0.029