MRAFU

Prompt

6.3.2.9

Ligases. Forming carbon-nitrogen bonds. Acid--amino-acid ligases.(peptide synthases). UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase.

AI Generated Sequence

500 AAs

MIPVGSFEGKRVAVLGLGRSGLAAARALEAGGAEVLAWDDNPAARAAAAAAGFAVVDLRTADAFAAVAALVTSPGIPYLTPKPHTVIAAARAAGVPVDNDIGLFFREFAARDGFEFDPVPVIAITGSNGKSTTTALIHHLLRWAGRRTQLAGNIGRGVLDLDPPEGGDVVVLELSSYQTDLARALDPDVAVFTNLSPDHLDRHGGFGGYFAAKRRLFEGGGPDRAIVGIDDAESGRFLARLGEQGEDGERIIRISVKELGGWGFDRRGLIDRAFAERRRGRRAEAIDLAAIGGLPGAHNHQNACAAYAAARALGLDPRAIADGLRSFRGLPHRSQRVGERGGVRFVNDSKATNADSAAKALSCFERIVWIAGGREKEGGLTALAPHFGNVAKAYLIGREAAEAFARELGAHVDECGTMDRAVAAAAAEAGEGETVLLAPACASFDQFANFEERGDAFVAAVEALPDGARIVGEGGRGGGGGGGGGGGGGGGGGGGGGGGG

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	89.6
NLMSIM	70.0
AACOMP	85.4
Seqdif (SeqID)	30.6 (WP_261493476.1)
Structdif (F-Target)	8.5 (5a5e A)

ProtNLM

Name	Score
D-glutamic acid-adding enzyme	0.298
6.3.2.9	0.273
UDP-N-acetylmuramoylalanine--D-glutamate ligase	0.245
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase	0.177
Meso-diaminopimelate-adding enzyme	0.001
Multifunctional fusion protein	0.001