MR5OD

Prompt

1.2.1.71

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. succinylglutamate-semialdehyde dehydrogenase.

AI Generated Sequence

499 AAs

MTHPALFIDGAWRPGEGEPLASRNPATGEPVWQGAGASAADVDAAVAAARAAFPAWSARPLEARIAIVERFAALLAERKEALAATIGRETGKPLWEARTEVAAMAAKVAISIRAYHERTGERAADMPDGRAVLRHRPHGVLAVFGPYNFPGHLPNGHIVPALIAGNTVVFKPSELTPKVAELTMRLWDDAGLPAGVLNLVQGERDTGIALAANPQIDGLFFTGSSHTGHLLHRQFAGRPEMILALEMGGNNPLVVADVADVDAAVHHAIQSAFISAGQRCTCARRLLVPQGAWGDAFLARFVDATARITVGAWDADPQPFMGAVISARAAGALLAAQARLLALGARPLLEMTRLDPAAGFVSPGIIDVTAVGDLPDEEHFGPLAQVVRYADFDAAVARANATAFGLSAGLLADDRALWDHFWWEIRAGIVNWNRPLTGASSAAPFGGVGASGNHRPSAYYAADYCAWPMASLEAPALTLPANLSPGLRFDPAAAAAAAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	96.0
NLMSIM	70.0
AACOMP	86.5
Seqdif (SeqID)	22.5 (WP_038798904.1)
Structdif (F-Target)	1.3 (4kna B)

ProtNLM

Name	Score
SGSD	0.264
N-succinylglutamate 5-semialdehyde dehydrogenase	0.263
Succinylglutamic semialdehyde dehydrogenase	0.243
1.2.1.71	0.205
Succinylglutamate-semialdehyde dehydrogenase	0.015
3.5.1.18	0.001