MR004

Prompt

1.2.1.70

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. glutamyl-tRNA reductase.

AI Generated Sequence

207 AAs
MNILTIGLNHKTAPVEIREKLSISEAQMHEALSTLVAQPHIGECAILSTCNRVEIYCVVDKHALGVEAITRFLSEHSHLPVEALTPHLYVHYDDDAIEHLFRVASGLDSMVLGETQILGQVKSAYLLAQEHKAVGTVLNHMFRQALSVAKRAHSETDIGAGAVSVSYAAVELGRQIFGDLTGKTVLIIGAGEMTELVAKHLYGSGAG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT97.0
NLMSIM90.0
AACOMP92.4
Seqdif (SeqID)38.6 (WP_062677879.1)
Structdif (F-Target)8.6 (4n7r A)

ProtNLM

NameScore
Glutamyl-tRNA reductase0.611
1.2.1.700.339
GluTR0.035
GlutR_N domain-containing protein0.003
Glutamyl-tRNAGlu reductase, N-terminal domain protein0.001
Glutamyl-tRNAGlu reductase0.001
Designed by MP, using an AMD MI250 GPU