MQZ6K

Prompt

1.3.1.12

Oxidoreductases. Acting on the CH-CH group of donors. With NAD(+) or NADP(+) as acceptor. prephenate dehydrogenase.

AI Generated Sequence

744 AAs

MSEPVFDRIALIGIGLIGGSIARAVREAGLAREIVGYARDPATLDRVRELGLCDEYTDDAAAAVEGADLVILAVPVGAMGAVAAEIAPALKPGAIVTDVGSVKGAVIDAVAPHLPDGVHFVPGHPLAGTEHSGPDAGFAELFRNRWCILTPPEGTDPAALDRLSAMWRALGANVEEMDARHHDLVLAVTSHLPHLIAYNIVGTASDLERVTESEVIKYSASGFRDFTRIAASDPTMWRDVFLANRDAVLEMLARFSEDLAYLQRAIRWGDGHALFDFFTRTRAIRRSWIEIAGQDAAPDFGRSGEDDEPTQAGPRAFDAIGRRIGVNKDVSLHRSIDFGALGEITSVGTGWAEAEADALTRAFGWDVVVIEGPDHGRVTITLGVHGLKGLPAPVEIYGNAGSIAHLLAGTLAAQADFVRLTGEASLTKRPMGDIAPRLYAMGATIEAGEGWHCPLTIRTGGKLARVDYTMDVAASQVSEVIAAGGEWAGDVTVTVEPAPTRDHTERMLARIYGPVTEVGGTVDLSEGGGLRAIDEIPAGDHESARFIVAAASIAEGADLLLEVGIHPNTRTGVINILRLMGADIALENRIVEDGPWEDLHVIRAGRWKGKDIPEDHVPLAIDEFPTVLFVAACAEGRTVLTGREELRVEKSDRIQMAEDAGDLAIGYRVPETPDGIIIEGSQIGGGDWIEAGGDRIAAISFTSVAALARTPMIRIGDANVRNTFPNFIALAEAGRQLRGEEAEA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	71.5
NLMSIM	95.0
AACOMP	90.7
Seqdif (SeqID)	49.5 (MVW85089.1)
Structdif (F-Target)	3.1 (4wji 2)

ProtNLM

Name	Score
1.3.1.12	0.394
Prephenate dehydrogenase	0.388
Prephenate/arogenate dehydrogenase family protein	0.042
Cyclohexadienyl dehydrogenase	0.038
1.3.1.43	0.018
Prephenate dehydrogenase/arogenate dehydrogenase family protein	0.017