MQZ3Y

Prompt

1.14.13.2

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. With NADH or NADPH as one donor, and incorporation of one atom of oxygen. 4-hydroxybenzoate 3-monooxygenase.

AI Generated Sequence

730 AAs

MKTQVAIIGAGPSGLLLGQLLHKAGIDNIILERQSPGYVLGRIRAGVLEQGTVDLLREAGVGERMHAEGLPHDGFEIAFDGRHFRIDLKGLTGGKVTVYGQTEVTRDLMDAREAAGLPTIYEAENVQLHDFDSDSPYVTYEKDGVTHRIDCDFIAGCDGFHGVSRQSIPESAIKTFERVYPFGWLGILSDVPPVSHELIYANHERGFALCSMRSPTRSRYYIQVPLDDKVEDWSDERFWNELKTRLPEHAAEKLVTGPSIEKSIAPLRSFVAEPMRFGNLFLVGDAAHIVPPTGAKGLNLAASDVHYLSQGLVEFYKEGSTEGLDGYSQICLARVWKAERFSWWMTSMLHRFPDTQAFDQRIQQAELDYLHSSEAGQSTIAENYVGLPMEDVGVVEEVQITPMHRVETAVRNLGLEFHMTPTTAVRDAIGSGPTFEPNMVVAQSGELERPLVLATKNIEHTGYNPVRAFDEPVVTWNKDGVEHVRIDCDFIAGCDGFHGVSRQSIPASAIKEFERVYPFGWLGILSDVPPVHEELIYANHPRGFALCSMRSPTRSRYYIQVPLSDEKVEDWSDDRFWNELKTRLPSEVAEKLVTGPSFEKSIAPLRSFVAEPMRYHGRLFLVGDAAHIVPPTGAKGLNLAASDVHYLSHGLKEHYENGETGLIDGYSQMCLARVWKAERFSWWMTSMLLHRFPDTQAFDQKIQEAELDYLVSSEAGQSTIAENYVGLPFE

Ligand/Cofactor

NADH

C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O

Validation Metrics

PLDDT	75.0
NLMSIM	90.0
AACOMP	95.7
Seqdif (SeqID)	23.2 (WP_095154785.1)
Structdif (F-Target)	2.0 (1cj2 A)

ProtNLM

Name	Score
1.14.13.2	0.587
4-hydroxybenzoate 3-monooxygenase	0.300
P-hydroxybenzoate hydroxylase	0.057
4-hydroxybenzoate hydroxylase	0.018
P-hydroxybenzoate 3-monooxygenase	0.008
FAD_binding_3 domain-containing protein	0.005