MQVO4

Prompt

1.21.98.1

Oxidoreductases. Catalyzing the reaction X-H + Y-H = 'X-Y'. With other, known acceptors. cyclic dehypoxanthinyl futalosine synthase.

AI Generated Sequence

245 AAs
MEELLALYRAAPLHALGAAADAVRRRLHPEHATSFIVDRNINYTNVCVADCKFCAFYRAPGDAKGWVLSLDEIDRKCAETLALGGTQIMFQGGLHPDLGIDYYEAHFAAIKARFPAITIHGLSAPEIAHMARISGLSVAEVLARLHAAGLDSLPGAGAEILADRVRDAIAPCKVSGERWLEVMRAAHALGLKSTATMMFGHVETPAERIEHLDMLRDVQDRTGGFRAFIPWSFQPENTPLLGHGG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT94.0
NLMSIM60.0
AACOMP91.3
Seqdif (SeqID)31.1 (WP_189233807.1)
Structdif (F-Target)5.8 (6xi9 A)

ProtNLM

NameScore
Dehypoxanthine futalosine cyclase0.552
CofH family radical SAM protein0.088
Radical SAM protein0.070
Cyclic dehypoxanthine futalosine synthase0.052
Radical_SAM domain-containing protein0.042
Cyclic DHFL synthase0.039
Designed by MP, using an AMD MI250 GPU