MQETT

Prompt

6.1.1.18

Ligases. Forming carbon-oxygen bonds. Ligases.forming aminoacyl-tRNA and related compounds. glutamine--tRNA ligase.

AI Generated Sequence

181 AAs
MSENEKKNNFIHDIIDADLRSGKHGGKVRTRFPPEPNGYLHIGHAKSICLNFGIADKYGGKCNLRFDDTNPSKEDIEYVESIKEDVHWLGFEWEKEITYASDYFDRLYEYAVELIKAGLAYVDDLSAEEIREYRGTLTAPGKNSPYANRSVEENLDLFERMRNGEFPEGSAVLRAAIDMAS

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT87.2
NLMSIM90.0
AACOMP90.8
Seqdif (SeqID)20.2 (MDI6638033.1)
Structdif (F-Target)9.5 (2re8 A)

ProtNLM

NameScore
Glutamine--tRNA ligase0.592
6.1.1.180.338
Glutaminyl-tRNA synthetase0.041
TRNA-synt_1c domain-containing protein0.009
GlnRS0.003
Glutamine--tRNA ligase/YqeY domain fusion protein0.002
Designed by MP, using an AMD MI250 GPU