MQCU0

Prompt

1.1.1.39

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. malate dehydrogenase (decarboxylating).

AI Generated Sequence

315 AAs

MKVAVLGAAGGIGQALALLLKLRLPAGSELALYDIAPVTPGVAVDLSHIPTAVEVKGFSGEDPTAALEGADVVLIPAGVARKPGMDRSDLFNINAGIVKSLIEKVAAVCPKACIGIITNPVNSTVAIAAEVLKKAGVYDKRKLFGVTTLDVIRSETFVAELKGLNVGDIRVPVIGGHSGVTILPLLSQVEGVSFTDEEVAALTKRIQNAGTEVVNAKAGGGSATLSMGAAACRFALSLVRGLQGEKVVECAYVEGDSEHATFFAQPVRLGKNGVEEILSYGDVSAFEQQALDGMLPTLEKDIQLGEEFVKGVDWV

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	91.2
NLMSIM	60.0
AACOMP	91.5
Seqdif (SeqID)	13.5 (WP_220761058.1)
Structdif (F-Target)	1.7 (6itl 2)

ProtNLM

Name	Score
Malate dehydrogenase	0.582
1.1.1.37	0.415
Homoserine dehydrogenase	0.000
NAD-dependent malate dehydrogenase	0.000
2.3.1.8	0.000
1.1.1.40	0.000