MQA3V

Prompt

2.1.1.67

Transferases. Transferring one-carbon groups. Methyltransferases. thiopurine S-methyltransferase.

AI Generated Sequence

218 AAs

MEPEFWHERWAAGRIGFHQDEVNPFLVRHWPALGLPAGARVFVPLCGKSLDMCWLAGQGHEVLGVELSELAVRDFFAEHGLAPEITTLPGAHRVYRAGDIELWCGDFFALTAADVAGCDAVYDRAALVALPPEMRARYAAHLARLLPAGGRGLLVTLDYPQAEMAGPPFAVPDAEVRALLAGGWEVRRLERPDVLAEHPRFVAKGVPSLVERVYRLAR

Ligand/Cofactor

S-adenosylmethionine

C[S+](CCC(C(=O)[O-])N)CC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O

Validation Metrics

PLDDT	95.3
NLMSIM	90.0
AACOMP	87.5
Seqdif (SeqID)	35.5 (WP_166224385.1)
Structdif (F-Target)	6.5 (2h11 B)

ProtNLM

Name	Score
Thiopurine S-methyltransferase	0.375
Thiopurine methyltransferase	0.374
2.1.1.67	0.242
Methyltransferase domain-containing protein	0.000
SAM-dependent methyltransferase	0.000
Ubiquinone biosynthesis O-methyltransferase	0.000