MQ6QY

Prompt

1.13.11.53

Oxidoreductases. Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. With incorporation of two atoms of oxygen. acireductone dioxygenase (Ni(2+)-requiring).

AI Generated Sequence

234 AAs

MARIVWKDGTLTDQNPEVKSDLEEGILDLEKIGVPFERWHADSEPEDPEAKEEILAYFDREIDALKAEGGFKTRDVISLSPDNPKLDEMRAKFLEAHHHTDDEVRFFVSGSGIFLHIKGDKVFEYLCEPGDFISVPAGTNHWFDMTGEKPFTAIRWFTEPEGWVGHYTGETIDSFQRPLEEDEKAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	76.4
NLMSIM	80.0
AACOMP	81.5
Seqdif (SeqID)	44.8 (MDV3254262.1)
Structdif (F-Target)	14.8 (4qgm A)

ProtNLM

Name	Score
1.13.11.54	0.125
ARD'	0.107
Fe-ARD	0.105
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase	0.104
Acireductone dioxygenase (Ni(2+)-requiring)	0.097
ARD	0.096