MQ1GC

Prompt

1.1.1.306

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. S-(hydroxymethyl)mycothiol dehydrogenase.

AI Generated Sequence

468 AAs

MSQTVKGVIARGKGEPVELVNIVVPDPGPGEVLVKIQACGVCHTDLHYREGGINDEFPFLLGHEAAGVVESVGPGVTNVAPGDFVILNWRAVCGQCRACKRGEPWYCFDTHNATQKMTLEDGTELTPALGIGAFAEKTLVHAGQCTKVDPAADPAAAGLLGCGVMAGLGAAMNTGNVTRGDSVAVIGCGGVGDAAIAGAALAGASKIIAVDIDDKKLDWAKNFGATHTVNSKETDVVEAIQELTDGFGADVVIDAVGRPETWKQAFYARDLAGTVVLVGVPTPEMKLEMPLLDVFGRGGALKSSWYGDCLPSRDFPMLIDLYLQGRLPLDKFVSERIGLDQVEKAFHKMHKGEVLRSVVVLDPRPGLGRETVVLEKEIVAAPTPVVKRTMPVVVKLVGGSKVVLKTDYGAGEKADEKKAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	78.5
NLMSIM	95.0
AACOMP	86.6
Seqdif (SeqID)	15.5 (WP_046363413.1)
Structdif (F-Target)	5.7 (5tnx A)

ProtNLM

Name	Score
S-(Hydroxymethyl)mycothiol dehydrogenase	0.816
1.1.1.306	0.074
Alcohol dehydrogenase	0.019
Mycothiol-dependent formaldehyde dehydrogenase	0.015
Aryl-alcohol dehydrogenase	0.008
NAD/mycothiol-dependent formaldehyde dehydrogenase	0.006