MPRMQ

Prompt

1.1.1.169

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. 2-dehydropantoate 2-reductase.

AI Generated Sequence

500 AAs

MKIAVLGPGAIGGYLGARLARAGHDVTLLDRGPHAEAIRRNGLTRDGTFEGRLTARATDPAELAGPADLVLVTVKAWQTLDAVRSLAPLLGPDTPVLCLQNGLGNHEELAALIGGRRVLGGTTHHAARLEGPGVVHHAGNGLTIFGELRGDGSYRRLADVLDGAGLDATWSENIRAELWRKLAVNCAINPLTALARCPNGELADHPAARRIGELVGEEAAVIGAAHGVEPGEDVLDVVGRVARATAENTSSMLQDVAAGRRTEIDYINGFVLRLGREHGIATPTNRLLTALVRRRESELRITGGTGRERELAELEARLAELEARLAELEARLAELEARLAELEARLAELEARLAELEARLAELEARLAELEARLAELEARLAELEARLAELEARLAELEARLAELEARLAELEARLAELEARLAELEARLAELEARLAELEARLAELEARLAELEARLAELEARLAELEARLAELEARLAELEARLAELEARLAELRARL

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	81.0
NLMSIM	95.0
AACOMP	80.4
Seqdif (SeqID)	49.2 (WP_021517496.1)
Structdif (F-Target)	4.4 (5ayv A)

ProtNLM

Name	Score
1.1.1.169	0.371
2-dehydropantoate 2-reductase	0.370
Ketopantoate reductase	0.253
1-deoxy-D-xylulose 5-phosphate reductoisomerase	0.000
Oxidoreductase	0.000
2.7.2.16	0.000