MPP68

Prompt

1.6.5.8

Oxidoreductases. Acting on NADH or NADPH. With a quinone or similar compound as acceptor. Transferred entry: 7.2.1.1.

AI Generated Sequence

145 AAs
MKKIVVLGGGFAGVELAGELADFVKTDLKKYFPNIDENMKITLVEASERILPAFPEKSQAYAQKQFVDRGVEVLTNTMVKEVKADGVVLKDGKKIPTDLVIAVGSVSNTFGTPGVKEHCFFLKEISDAQHIRNRILNCFEKAYLP

Ligand/Cofactor

NADH

C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O

Validation Metrics

PLDDT83.2
NLMSIM70.0
AACOMP90.6
Seqdif (SeqID)54.4 (GFZ48217.1)
Structdif (F-Target)22.9 (4nwz 3)

ProtNLM

NameScore
Pyr_redox_2 domain-containing protein0.524
NADH dehydrogenase0.119
FAD-dependent oxidoreductase0.100
NAD(P)/FAD-dependent oxidoreductase0.060
Pyridine nucleotide-disulfide oxidoreductase0.051
1.6.99.30.025
Designed by MP, using an AMD MI250 GPU