MPMSE

Prompt

2.3.1.285

Transferases. Acyltransferases. Transferring groups other than amino-acyl groups. (13S,14R)-1,13-dihydroxy-N-methylcanadine 13-O-acetyltransferase.

AI Generated Sequence

563 AAs

MSDERIAVIGMACRFPGADSVEEFWRNLVEGRDAITEVPADRWDLDAYYDPDTPAPGKTYVRGGGFLDDIDAFDAAFFGISPREAELMDPQQRLFLEVAWEALEDAGYDPARLAGSRTGVFVGIGNDGYLLNLLADPRRDVDAYQTLGNAKDFLATRVSYLLDLRGPAFTVQTACSSSLVAVHLACQSLLSGECDMALAGGVSIHLPQHTGYLYSKAGMLSPDGHCRAFDARANGTVGGEGVGVVVLKRLADAVADGDHIHAVIRGSAVNNDGAAKVGYTAPSVAGQAAVIAEAQAVAGVDARTIGYVEAHGTATALGDPIEVAALTRAFGRDTRRGGFCAIGSVKTNIGHLDAAAGVAGLIKTVLALHHRRIPPTLHFERPNPHIDFAASPFYVNTALAPWETGGTPRRAGVSSFGVGGTNAHVVLEEAPAEPAPAPAPAPAPRPHLLPLSARTAAALAEATARLADHLAAHPDADLADVAYTLQTGRRHFDHRRAVVADDRAELVAALRAAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG

Ligand/Cofactor

acetyl-CoA

CC(=O)SCCNC(=O)CCNC(=O)C(C(C)(C)COP(=O)(O)OP(=O)(O)OCC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)O)O

Validation Metrics

PLDDT	87.6
NLMSIM	60.0
AACOMP	86.0
Seqdif (SeqID)	35.0 (HNP74709.1)
Structdif (F-Target)	12.2 (6mhk A)

ProtNLM

Name	Score
Beta-ketoacyl synthase	0.196
SDR family NAD(P)-dependent oxidoreductase	0.155
Acyl transferase domain-containing protein	0.132
Type I polyketide synthase	0.091
Polyketide synthase	0.070
Acyltransferase domain-containing protein	0.052