MPLBR

Prompt

1.1.1.90

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. aryl-alcohol dehydrogenase.

AI Generated Sequence

412 AAs

MKAAVLYEPGKPLVIEEIEVDPPGPGEVLVRIEAAGLCHSDLSVMDGALPLPLPMVLGHEGAGIVEAVGPGVTHLAPGDHVVLTFLPACGHCEACLTGRPALCTAGQPVNRTGALLRTGGTLTRTGGTLRHFLGVSSFAETAVVHEASVVKIAPDVPLELAGLIGCGVLTGAGAVLNTARVRPGSTVAVFGCGGVGLSAIMGAAIAGAGRIIAVDVAPAKLALARELGATHTVNAAAGDPVARIRELTGGGADFALECVGRAATTETAWAATRRGGTAVLVGLPAPDAQTFSVPALTLAAGGRTLKGSLYGGARPIPRLVELYRAGRLPLDALVTHRLPLAAINEAFDLLAAGRAIRPVIVFGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	89.4
NLMSIM	70.0
AACOMP	80.9
Seqdif (SeqID)	43.1 (PZN12673.1)
Structdif (F-Target)	4.7 (1f8f A)

ProtNLM

Name	Score
Alcohol dehydrogenase	0.542
Zn-dependent alcohol dehydrogenase	0.076
Zinc-binding dehydrogenase	0.054
1.1.1.1	0.042
1.1.1.284	0.028
Alcohol dehydrogenase D	0.026