MPJFQ

Prompt

1.20.4.4

Oxidoreductases. Acting on phosphorus or arsenic in donors. With disulfide as acceptor. arsenate reductase (thioredoxin).

AI Generated Sequence

105 AAs
MATITVTDASFDAEVLKSAEPVLVDFWAEWCGPCRMIAPALDEIAAEMADKVKVVKVNVDENPNTAAELGIRSIPTLMLFKDGELVARIVGARPKAALTAWLGKN

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT93.2
NLMSIM70.0
AACOMP89.0
Seqdif (SeqID)22.5 (WP_019403177.1)
Structdif (F-Target)2.2 (2yn1 B)

ProtNLM

NameScore
Thioredoxin0.997
Thioredoxin 10.001
Thioredoxin TrxA0.000
Thioredoxin domain-containing protein0.000
Thioredoxin C-10.000
Thioredoxin-10.000
Designed by MP, using an AMD MI250 GPU