MPID6

Prompt

1.2.1.27

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. methylmalonate-semialdehyde dehydrogenase (CoA acylating).

AI Generated Sequence

252 AAs

MTTIGHFINGKHVEGTSGRFADVFNPATGEVQGKVPLASKEEVDRAVAAAKAAFPAWADTNPQRRARVMFKFRELVNKNHDELALLISREHGKTFADAKGEVQRGLEVVEFACGAPHLLKGEFTNGAGPGIDVYSMRQPLGVVAGITPFNFPAMVPMWMFGPAIACGNTFVLKPSERDPSVPLRLAELFKEAGLPKGVFQVVNGDKEAVDAILDHPDIKAIGFVGSTPIAQYIYETGTANGKRVQCFGGAKN

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	96.3
NLMSIM	95.0
AACOMP	91.5
Seqdif (SeqID)	21.8 (WP_263952964.1)
Structdif (F-Target)	4.3 (7kqv 2)

ProtNLM

Name	Score
Methylmalonate-semialdehyde dehydrogenase (CoA acylating)	0.344
Aldehyde dehydrogenase family protein	0.188
CoA-acylating methylmalonate-semialdehyde dehydrogenase	0.146
Methylmalonate-semialdehyde dehydrogenase	0.114
1.2.1.27	0.100
Aldedh domain-containing protein	0.031