MPH8O

Prompt

1.1.1.368

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. 6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase.

AI Generated Sequence

341 AAs

MKAAVIEGPGKVRVEEVEVPEPKGPGEVLVRVKATGICHSDLHGYKGDFPEVPGPVILGHEGAGIVEEVGPGVTNWKVGDRVVVPFVPGCGHCEYCRSGQQNLCENQQGPNGFHWGGSFAEYVVVPADYNVVKLPEGVDFATAASLGCRFATAYHAVKNAGVKPGEWVAVHGCGGVGLSAVQGAKIMGASRIIAVDINEDRLELAKKFGATHTINAREGDVVEEVRELTGGKGAHAVLEAVGVPATFNQSIQSVRRGGRHVQVGLMHGDVEIPINTVIWKELQLQGSHMGTRKDYPRALELIASGKIDVKGLITHRFSLEEINEGFDAMAKGEMIGKVLTM

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	89.2
NLMSIM	60.0
AACOMP	88.7
Seqdif (SeqID)	47.5 (WP_326641399.1)
Structdif (F-Target)	4.0 (6iqd A)

ProtNLM

Name	Score
Alcohol dehydrogenase	0.629
1.1.1.1	0.088
Zinc-dependent alcohol dehydrogenase	0.046
PKS_ER domain-containing protein	0.029
Alcohol dehydrogenase GroES domain protein	0.026
Zinc-binding dehydrogenase	0.025