MPD7V

Prompt

1.1.1.57

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. fructuronate reductase.

AI Generated Sequence

499 AAs

MKTLNAVLPANVTQPGWDRSQLAAKIVHLGCGAFHRAHQAVYTDHLLNEHDSDWGICEVNLFGGEQLIQNLQKQQCLYTLVAEKGADQTTAVIVGSVKEALHANIDGIEAILAKMCEPQTAIVSLTVTEKGYCHSPATGELLLNHPLIVHDLQNPQKPSAIGFIVEALRRRREAGLPAFTLSDCDNMRENGHVVRAVVVNLVARLDPALAAWIAENVTFPATMVDRIVPAATEETLAEISAATGVADPCAIACEPFRQWVIEDNFVAGRPAWDKVGAQLVSDVVPWEMMKLRMLNGSHSFLAYLGYLGGYEHINDCMQDEHYRHAANALMLEEQAPTLQVMGVDLNAYADLLIERFSNPALRHRTWQIAMDGSQKLPQRMLDSVRWHLANGSRWSCLALGVAGWMRYVGGVDEQGNAIEVRDPLLAEIQAFVNSSYQGDARVQALLSIRAIFGDDLPQNPEFVAAVTQAYASLKSHGARATVAAYCAEQGLAAQAAQAA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	89.8
NLMSIM	90.0
AACOMP	93.0
Seqdif (SeqID)	28.8 (EHY6455872.1)
Structdif (F-Target)	1.6 (4im7 A)

ProtNLM

Name	Score
Fructuronate reductase	0.559
1.1.1.57	0.227
D-mannonate oxidoreductase	0.060
1.1.1.-	0.031
Mannitol dehydrogenase family protein	0.028
Polyol:NADP oxidoreductase	0.027