MOTQR

Prompt

3.2.2.9

Hydrolases. Glycosylases. Hydrolyzing N-glycosyl compounds. adenosylhomocysteine nucleosidase.

AI Generated Sequence

233 AAs
MKKIGIIGAMEQEIELLKEKMKNEEKIEIAGFDFIKGKLNGKDIIVLKSGIGKVNAAITTALMIEKYKPDAIINTGVAGGLNKDLNIGDVVIATDLVYHDVDATAFGYEKGQIPGMPTIFEADKKLIEKAKEAIKNEKLNILHEGRILSGDSFVTSKEKIEKIKEEFKGLACVEMGGAAVAQVCYLFKVPFIVIRAISDIADGNANVDFEKFNLEASKRSAEVVIKFVEKLKK

Ligand/Cofactor

adenosylhomocysteine

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CSCCC(C(=O)O)N)O)O)N

Validation Metrics

PLDDT90.8
NLMSIM60.0
AACOMP85.5
Seqdif (SeqID)50.2 (WP_069718535.1)
Structdif (F-Target)1.8 (3eei B)

ProtNLM

NameScore
SAH nucleosidase0.125
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase0.114
5'-methylthioadenosine nucleosidase0.108
DOA nucleosidase0.107
MTA nucleosidase0.094
5'-deoxyadenosine nucleosidase0.070
Designed by MP, using an AMD MI250 GPU