MOP08

Prompt

3.7.1.11

Hydrolases. Acting on carbon-carbon bonds. In ketonic substances. cyclohexane-1,2-dione hydrolase.

AI Generated Sequence

500 AAs

MTTIRLTTAQALVRFLDAQYVEVDGKKLPFVKGIFTIFGHGNVLGLGEALEQAGDHLPVYQGRNEQGMAHAAIAFAKQKLRRQIMACTSSIGPGATNMVTAAATAHANRIPVLLLPGDVFATRQPDPVLQQIEQFHDLTISTNDAFRPVSKYWDRITRPEQLMTAAPRAMRVLTDPAETPGATLCLSQDVQGEAWDYPESFFAKRVHRIDRPRPDAAALADAVAAILAAKKPLIIAGGGVRYSGAEAALKAFAEATGIPFAETQAGKGSLAWSHPLNVGGIGVTGSLAANLIAREADLVIGVGTRYTDFTTGSKWLFQHPEVRFLTLNVGRFDAHKLDALPVVADAREGLAALAAGLGGWQVPSGFTAEIAAAKAAWLAETDRLYTEALGTLPTQAQVLGALNRHLDPDAIVLNAAGTLPGDLHKLWRTRKPNTYHVEYGFSCMGYEIAGALGVKMAEPDREVVVMVGDGSYLMLHSELVTSVQEHKKLTIVLLDNAGFG

Ligand/Cofactor

cyclohexane-1,2-dione

C1CCC(=O)C(=O)C1

Validation Metrics

PLDDT	92.4
NLMSIM	85.0
AACOMP	92.8
Seqdif (SeqID)	31.9 (WP_025950765.1)
Structdif (F-Target)	12.0 (3eya G)

ProtNLM

Name	Score
3.7.1.22	0.359
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (Decyclizing)	0.289
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase	0.172
Thiamine pyrophosphate protein central region	0.034
3.7.1.-	0.021
Acetolactate synthase	0.019