MOOZT

Prompt

1.1.1.135

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. GDP-6-deoxy-D-talose 4-dehydrogenase.

AI Generated Sequence

512 AAs

MKISVFGLGYVGAVCAGCLAKMGHEVIGVDISKDKIDLINNGKSPIYEPGLEELLQKGIQTGKLRGTTDFAEAIRTADVSMICVGTPSKKNGDLDLTYIESVCREIGYVIDKDLTPDHTIVVKSTVYPGTANNVIIPLIEDCSGKKAGVDFGVSNPEFLREGTAVKDYFDPPMTVIGGFDPKASGDLLAHLYEEIDAPIIKTDIAVAEMIKYTSNVFLATKISFINEISNICKAVGVDGHEVMDVACHDKANIGRQYMRPGFAFGGSCLPKDVRALTYRASRLDVEARLLASVMRSNESQVQKAFDIMADYDKRKVALLGLSFKAGTDDMRESPLLELAEMLIGKGFDLHIYDPNVNEARVHGALKDIYSEKTIPHVSLLTSDFDQVINDSDVIVLTGNRDEFRALANAKTPEGKRVIDLFGNMYNATEEDRAEGIVCGIGDRACRNGVHNIAQYGYTGIVAARQYSMAKQAAAAAHHGAKAILLDGMMNKATEEDAREAGIVCGVGKRACY

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	80.7
NLMSIM	60.0
AACOMP	93.5
Seqdif (SeqID)	20.9 (WP_248688222.1)
Structdif (F-Target)	6.7 (3vtf 2)

ProtNLM

Name	Score
1.1.1.22	0.583
GDP-mannose 6-dehydrogenase	0.181
UDP-glucose 6-dehydrogenase	0.180
1.1.1.132	0.041
Nucleotide sugar dehydrogenase	0.003
UDP-glucose/GDP-mannose dehydrogenase family protein	0.001