MOO66

Prompt

1.7.1.7

Oxidoreductases. Acting on other nitrogenous compounds as donors. With NAD(+) or NADP(+) as acceptor. GMP reductase.

AI Generated Sequence

377 AAs

MRIEDLGLGKFDVLVARPRKSTLKSRSEVDLQRTFTFRNSKQTYTGIPMIAANMDTVGTFEMAKVLAEHHVMTAIPKHYTVEQWVDFVKSNPDAVLDHIVASGSVGSADFEKLTKILAEIPQIKFICLDVANGYSSHVFEYAKKVREQFPTHTIMSGNVATGEMVEELILSGADIIKVGIGPGGVCTGRVKVGVGYPQLSAVIECADAAHGLDKGLIIGDGGCTPGDVAKAFGAGADVVLLGGMLAGHEECSGEIIEENGKKVKLFYGMSLETAMQKHTGGVAEYRASEGRTVDVPFKGPVESTIRDILGGLRSTCTYVGAASIKELKGRTTFIRVAEQQNRVFGKEFSEIAEQDPNDFILFQADDVNEDGLVHDQY

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	85.4
NLMSIM	90.0
AACOMP	93.1
Seqdif (SeqID)	26.4 (XP_004549255.1)
Structdif (F-Target)	1.9 (2c6q H)

ProtNLM

Name	Score
GMP reductase	0.443
Guanosine 5'-monophosphate oxidoreductase	0.177
1.7.1.7	0.149
Guanosine monophosphate reductase	0.110
GMPR	0.102
GMP reductase 2	0.003