MOJY0

Prompt

7.2.4.3

Translocases. Catalysing the translocation of inorganic cations. Linked to decarboxylation. (S)-methylmalonyl-CoA decarboxylase (sodium-transporting).

AI Generated Sequence

297 AAs
MELSLLLLLLLAVAVGLNLLTRRLGLPTPLLLQVVGLAVGLLPPGIHVDLDPELLLLALLPPLLFADALRVSLGDFRRNWRPILLLAVGVVLFTTFVVGTLLWWLVPSVPWAAALLLGAVISPTDPVAVGAVARRLGLPRRTMTMIAGESLFNDGTGLVFTRLVVAAATGASFSWGAVARFLLRVVVGGVVGGIVVGLVLGLLRRLLGDDPLEVLLTLLQPYAAYLAAEHLHVSGVLATVACGLILGRGLARRLSPATQRYTHHNWQTLAYALNGLVFLLLGLQVRLISGLDDEEGR

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT93.9
NLMSIM70.0
AACOMP82.1
Seqdif (SeqID)51.8 (MBK5305944.1)
Structdif (F-Target)6.7 (8j2m B)

ProtNLM

NameScore
Sodium:proton antiporter0.362
Na+/H+ antiporter0.348
Sodium/proton antiporter (CPA1 family)0.088
Sodium/proton antiporter, CPA1 family0.076
Na_H_Exchanger domain-containing protein0.020
Sodium, potassium, lithium and rubidium/H(+) antiporter0.016
Designed by MP, using an AMD MI250 GPU