MOISE

Prompt

1.1.1.271

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. GDP-L-fucose synthase.

AI Generated Sequence

366 AAs

MSDSRIYVAGHRGMVGSAIVRRLEARGYTNLVTRTHAELDLTDRAAVEAFFAEERPDVVFLAAAKVGGIVANNTYPADFIYDNLMIQTNVIHAAHAAGVRKLLFLGSSCIYPKLAPQPMREDALLTGELEPTNEPYAIAKIAGIKLCESYNRQYGTDYRSVMPTNLYGPGDNFHPENSHVIPALIRRFHEAKAAGAPEVTVWGSGTPRREFLHVDDMADACVFLMELADGEPMHVNVGTGVDVTIRELAETIAAVVGYRGELVWDASKPDGTPRKLMDVSRLHALGWHATISLRDGLAAAYQWFRDNGGRIRGEGRGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	86.6
NLMSIM	75.0
AACOMP	85.1
Seqdif (SeqID)	25.4 (WP_068858281.1)
Structdif (F-Target)	4.3 (1bsv A)

ProtNLM

Name	Score
GDP-L-fucose synthase	0.469
GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase	0.328
1.1.1.271	0.195
NAD-dependent epimerase/dehydratase family protein	0.001
GDP-L-fucose synthetase	0.001
GDP-6-deoxy-D-mannose-3,5-epimerase-4-reductase	0.000