MOHXL

Prompt

1.20.4.4

Oxidoreductases. Acting on phosphorus or arsenic in donors. With disulfide as acceptor. arsenate reductase (thioredoxin).

AI Generated Sequence

106 AAs
MSTINVTDNTAFDEVLKSVEPVVVDFWAEWCGPCKQIGPALDEISAEYGDRVKIVKLNVDENPETAAKYGIRGIPTLMLFKDGELVQSIVGARPKALLTGWLEGNL

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT87.5
NLMSIM95.0
AACOMP92.5
Seqdif (SeqID)33.0 (WP_092684549.1)
Structdif (F-Target)3.6 (2yn1 B)

ProtNLM

NameScore
Thioredoxin0.993
Thioredoxin 10.002
Thioredoxin domain-containing protein0.001
Thioredoxin C-10.000
Thioredoxin-10.000
Thiol reductase thioredoxin0.000
Designed by MP, using an AMD MI250 GPU