MOGQ4

Prompt

6.2.1.45

Ligases. Forming carbon-sulfur bonds. Acid--thiol ligases. E1 ubiquitin-activating enzyme.

AI Generated Sequence

998 AAs

MDTKEIDESLYSRQLYVLGHEAMKRMATSNVLIVGLKGLGVEIAKNIALAGVKSVTLHDPKPVAISDLSSQFFLREEDVGKNRAEAVPARLAELNAYVPVTVHTGDLVTDLSQLKDYQVVVLTETPLKEQLAINDFCHSKNIYFIIADTRGLFGSVFCDFGEKFTVGDPTGETPLSGIIAGITKDEGIVTCLDETRHGLEDGDYVTFSEVQGMTELNGCEPRKITVLGPYTFSIGDTSGLGKYKRGGIFTQVKMPKFINFKPLSEQLKEPEFLISDFAKFDRPQQLHVGFQALHAFAEKHGRLPRPWNEEDAQEVLAIAKNIAAETGLEVEELDEKLIKELSYQARGDLNPMAAFFGGIAAQEVLKAVSGKFTPIKQWLYFDSLESLPTTVERTEEDCKPIGSRYDGQIAVFGKTFQEKIANLRQFLVGAGAIGCEMLKNWAMIGLGTGPEGKIFVTDMDTIEKSNLNRQFLFRPKDVGKLKSECAAAAVQAMNPDLKIEIAMEDRVGPDTEHIFNEDFWESLDGVTNALDNVDARTYVDRRCVFFRKPLLESGTLGTKGNTQVVIPHLTESYSSSQDPPEKSFPICTLKSFPNRIEHTIQWAKDLFEGLFKQPAENVNLYLSQPNFVEATLKQAGQPKEILENIYRSLVTDRPLTFEDCIVWARLQFEKQYNNAIQQLLYNFPKDKVTSSGAPFWSGPKRAPDPLKFDINNDTHLGFIVAAANLHAFNYGIKGGVDRAYYREVLDNMIVPEFTPRSGVKIQATDKELDPNNQASFDDNSEIEKLIAELPSPKTLAGFKLNPVEFEKDDDSNHHIDFITAASNLRAENYGIEPADRHKTKFIAGKIIPAIATTTALVTGLVCLELYKIIDGKDDIEQYKNGFVNLALPFFGFSEPIAAPKVEYKGKEWTVLWDRFEIKGEDMTLKEFIDHFKEKELEITMLSYGVSMLYASFMPPAKLKERMPLKMSELVETISKKPIPEHVKKVYVDPETGPERKKK

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	87.5
NLMSIM	70.0
AACOMP	94.1
Seqdif (SeqID)	24.0 (KAG2416837.1)
Structdif (F-Target)	5.1 (6dc6 A)

ProtNLM

Name	Score
UBA_e1_C domain-containing protein	0.269
Ubiquitin-activating enzyme E1	0.199
Ubiquitin-activating emzyme E1	0.187
Ubiquitin-activating enzyme E1 1	0.099
Ubiquitin activating enzyme	0.032
Ubiquitin-like modifier-activating enzyme 1	0.017