MOCJQ

Prompt

1.14.16.2

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. With reduced pteridine as one donor, and incorporation of one atom of oxygen. tyrosine 3-monooxygenase.

AI Generated Sequence

295 AAs

MPDKKSSELDKCNQLVTKYDPDLDADHPGFSDQVYRQRRKYIADIAFNYKHGDPIPRVEYTEEEIKTWQTVYRTLKSLYPTHACKEHLKLFSLLEKYCGYNEDNIPQLEDVSRFLKECTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASKPMHSPEPDVCHELLGHVPMLADPEFAQFSQEIGLASLGASDEYIKELTKEELKKLKELKEKLKELEKELKELEKELKEKEKELKEKEKELKEKEKELKEKEKELKEKEKELKEKEKELKEKEKELKEKEKELKEKEKEKE

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	89.0
NLMSIM	70.0
AACOMP	80.2
Seqdif (SeqID)	16.5 (NWI62675.1)
Structdif (F-Target)	32.8 (7zif A)

ProtNLM

Name	Score
Tyrosine hydroxylase 2	0.192
BH4_AAA_HYDROXYL_2 domain-containing protein	0.187
Tyrosine hydroxylase 1	0.096
Tyrosine 3-monooxygenase	0.091
Tyrosine 3-monooxygenase-like	0.084
1.14.16.2	0.052