MO9BC

Prompt

1.13.12.16

Oxidoreductases. Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. With incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases). nitronate monooxygenase.

AI Generated Sequence

202 AAs
MTTPLLERLGIEYPIVQGGMFWASGARLAAAVSNAGGLGFITGGLPLPEELREHIARCRELTDRPFGVNLMLPLAPPEEYLAVVLEKVPEVVTFSAGRPAPYTEALHAAGKIVVSYVTSVRHAQKAQKLGAAALVAEGFEAGGHIGREETSMLVLVPAVREAVGGPVIAAGGIATDGSMAAALALGAEGVQMGTRFLASREA

Ligand/Cofactor

FAD

CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)CC(C(C(COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O)O

Validation Metrics

PLDDT94.6
NLMSIM90.0
AACOMP88.4
Seqdif (SeqID)40.5 (MBK6629024.1)
Structdif (F-Target)4.3 (5gvj 2)

ProtNLM

NameScore
Nitronate monooxygenase0.471
2-nitropropane dioxygenase0.160
1.13.12.160.056
Enoyl-[acyl-carrier-protein] reductase0.042
NMO domain-containing protein0.037
Enoyl-[acyl-carrier-protein] reductase FabK0.029
Designed by MP, using an AMD MI250 GPU