MO7QH

Prompt

1.14.11.28

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors. proline 3-hydroxylase.

AI Generated Sequence

500 AAs
MQNLDYYQTMSGVKEADFLDLEAQPHMQEFRLGVRLYDEEQPLAAIEHLERALQEYFVADEDCRALCEGPYDYDGYNYLEYNADLFQAITDHYIQVLSCKQNCVTELASHPGSRKPLEDFLPSHYNYLQFAYYNIGNYTKAIECAKTYLLFFPNDEVMNQNLAYYTAMLGEDIAKSIKPREKAIDYIRQSLLEKEHLFFAYDVFGIPYVDPDTWTPEEVIPKRLREKQKERETAVRISQEIGNLMKEIETLVEEKKKESMDVSRLFREGGPLLYESIKLTMNSQVLNGSQRVVMDGVISDEECRELQRLTNAAALSGDGYRGKTSPHTPNEMFYGVTVLKALKLGQEGKVPLQSAHLYYNVTEKVRHMIESYFRLDTPLYFSYTHLVCRTAIDGQQEKRNDLSHPVHVDNCILNAEALNCIKEPPAYTFRDYSALLYLNGDFEGGNFYFTELDAKTVTAEVKPQCGRMVAFSSGTENPHGVKAVTKGQRCAIALWFTLDP

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT84.2
NLMSIM85.0
AACOMP93.5
Seqdif (SeqID)12.2 (XP_006904062.1)
Structdif (F-Target)19.4 (4j25 E)

ProtNLM

NameScore
Procollagen-proline 3-dioxygenase0.696
1.14.11.70.270
Prolyl 3-hydroxylase 10.024
P3H1 hydroxylase0.003
Proline hydroxylase0.001
Prolyl 3-hydroxylase 20.000
Designed by MP, using an AMD MI250 GPU
EC Repo - MO7QH | 310.ai