MO7BV

Prompt

1.3.1.21

Oxidoreductases. Acting on the CH-CH group of donors. With NAD(+) or NADP(+) as acceptor. 7-dehydrocholesterol reductase.

AI Generated Sequence

298 AAs

MAAKHKQKPGERRRGKLVYDKTTQQVPWGRAWEVDWWSLASIFFLMLFAPLVVYYFIMSCDQYHCSLTDPLLDLLTGKASLSDIWAKTPPTTYRALGIYTAWVTFQVLLYWTIPDFCHKFLPGYVGGVQEGALTPAGVVNKYEINGLQAWIITHALWFAAAYYFHWFSPTIIFDHWIPLLWCANILGYSVSTFAMIKGYFFPTNAEDCKFGGFTGNFFYDYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWTLINLSYAAKQQELYGQVTNSMILVNVLQALYVLDFFWHEAWYLKTII

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	83.7
NLMSIM	95.0
AACOMP	90.8
Seqdif (SeqID)	15.8 (NXW56523.1)
Structdif (F-Target)	30.1 (4quv A)

ProtNLM

Name	Score
7-dehydrocholesterol reductase	0.658
DHCR7 reductase	0.058
DHCR7	0.050
7-dehydrocholesterol reductase-like	0.026
Delta(14)-sterol reductase	0.016
7-dehydrocholesterol reductase,	0.012