MO6VW

Prompt

1.13.11.17

Oxidoreductases. Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. With incorporation of two atoms of oxygen. indole 2,3-dioxygenase.

AI Generated Sequence

501 AAs

MKPPVPSLADYGVSPEHGFLPRDLPLERLPDPYYEKWEAIAANLPQLILSRRLRGQVDRMPVLSTVYLHDYHEWRRAYVLLSFMAHGYIWGGDEPAERLPPRISVPLLEVSEHLELPPVATYAAVCLTNWKRIFDPEDIDNLENLATLNTFTGSLDESWFYLVSVAIEARGAPAIKLMLTALQAARDGDRAAVTECLRTFARCIDEMGTLLERMHEHCDPHIFYHRIRPFLAGWKNMAEAGLPNGVIYEDGTGEEPYRQYSGGSNAQSSLIQFFDILLGVEHRPTGEDKASEDSQGSEPAPKHGFLREMRRYMPGPHRRFLEHVGAVANIREYVLRHRDDQRLAAAYNACLAMLVALRDKHIQIVTRYIIVPSAKESRSRSRSPSVGATRLTNVGSVAAPAKKDLGTGGGTALMPFLKQARDETGEPAIEAWARRVLPDSSRPAFDAGSLAFKAAVDKDASLKGVSGTWDVSDDEGGGLCWTYEPEAFQGWGLDCDAPLPA

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	81.8
NLMSIM	90.0
AACOMP	94.5
Seqdif (SeqID)	33.4 (XP_009251759.1)
Structdif (F-Target)	4.2 (4u74 B)

ProtNLM

Name	Score
Indoleamine 2,3-dioxygenase	0.424
Indoleamine 2,3-dioxygenase subfamily	0.367
Indoleamine 2,3-dioxygenase family protein	0.041
Indoleamine 2,3-dioxygenase alpha type	0.012
Indoleamine-dioxygenase subfamily	0.009
Indolic compounds 2,3-dioxygenase-like protein	0.006