MO45Z

Prompt

1.1.1.145

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. 3beta-hydroxy-Delta(5)-steroid dehydrogenase.

AI Generated Sequence

537 AAs

MKKILVTGGSGFLGRHIVEQLLKEGHEVVRIFDLKKPEELKELGVEYVEGDITDKEKVKEACEGVDCVIHTASIIDVFGWNHETIHKVNVKGTQNLIEACKEAGVKKLVYTSTMGVVFPNGKDIFNGDETLPYVETHMDAYPETKAIAEALVLKANGGKLLTCALRPAGIWGEGDKQLLPRVARALKNGKSKFQIGDGKNLVDFTYVENVAWAHILAAEKLTKGGAHIAGQAFYINDGTPHKSFDFTNRILWKLGYEPDPRILPYKLAYMIAFLNEVVYFLLGRPIGFQPRFTRFEVYTTCTTRYFSIEKAKRDLGYEPIVGLEEGIKRTVEWFSGLVEKRKGKLDYLFGGKGKVADTLLWDLKKRLTAVLGPGVVGYIGYTAGKGTTFGGEETLPYVPTHLDAYNETKAIAEALVLKANGGKLLTCALRPAGIWGPGDKQLVPGLVRAAKNGKSKFLIGDGKNLVDFVYVENVAWAHILAARALKDGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	77.2
NLMSIM	70.0
AACOMP	85.9
Seqdif (SeqID)	53.0 (XP_012749039.1)
Structdif (F-Target)	10.8 (3aw9 2)

ProtNLM

Name	Score
3Beta_HSD domain-containing protein	0.505
NAD-dependent epimerase/dehydratase family protein	0.068
3-beta hydroxysteroid dehydrogenase	0.056
3-beta hydroxysteroid dehydrogenase/isomerase	0.047
NAD(P)-dependent steroid dehydrogenase	0.036
NAD(P)-dependent steroid dehydrogenase-like protein	0.025