MO2EP

Prompt

1.2.1.95

Oxidoreductases. Acting on the aldehyde or oxo group of donors. With NAD(+) or NADP(+) as acceptor. L-2-aminoadipate reductase.

AI Generated Sequence

491 AAs

MSTPDLPSSLDWSGYRGAIHDIFAANAEKFPDRPCVVETKSTEREFTYRQIDEASNVLAHHLVAAGIQRGDVVMIYAYRGVDLVVAFMGVLKAGGTFSVIDPLYPPARQNIYLNVAQPRALVVIEKATQDAGPLSETVRKYIDENLELRTEIPALALRDDGSLTGGALDGQDVLADTQLKASETPGVVVGPDSIPTLSFTSGSEGRPKGVLGRHFSLAYYFDWMAERFGLSENDKFTMLSGIAHDPIQRDIFTPLFLGAQLLVPAKEDIQHERLAEWMREYEATVTHLTPAMGQILVQGATAQFPSLHHAFFVGDILTKRDCRALQNLAPNVNVMNSYGTTETQRAVSYYEIPSRSEDPNYLNTMKDVIPAGRGMVDVQLLVVNRNDRTKICAVGEVGEIYVRAGGLAEGYLGLPELNAEKFVTNWFVDDQKWVEEDQKNVASKNEEPWREFYKGPRDRMYRSGDLGRYTPSGDVECVGRADDQVKIRGFR

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	84.6
NLMSIM	80.0
AACOMP	96.1
Seqdif (SeqID)	21.8 (GLA77998.1)
Structdif (F-Target)	5.1 (7ywk B)

ProtNLM

Name	Score
1.2.1.95	0.390
Alpha-aminoadipate reductase	0.307
1.2.1.31	0.163
L-aminoadipate-semialdehyde dehydrogenase	0.119
2-aminoadipate aminotransferase	0.001
2-oxoglutarate dehydrogenase E1 component	0.001