MNUJ2

Prompt

3.5.2.17

Hydrolases. Acting on carbon-nitrogen bonds, other than peptide bonds. In cyclic amides. hydroxyisourate hydrolase.

AI Generated Sequence

117 AAs
MKKLTTHVLDTAAGKPAAGLAVELYRLDGAERRLLKAATTNADGRVDAPLLAGEDFAAGTYRLVFHAGDYFAAQGVTLPEPAFLDVVEIRFGIADAAAHYHVPLLLSPWSYSTYRGS

Ligand/Cofactor

hydroxyisourate

C12=NC(=NC1(C(=O)NC(=O)N2)O)[O-]

Validation Metrics

PLDDT90.3
NLMSIM90.0
AACOMP88.3
Seqdif (SeqID)24.3 (WP_151986144.1)
Structdif (F-Target)2.0 (4q14 B)

ProtNLM

NameScore
HIUHase0.267
5-hydroxyisourate hydrolase0.260
3.5.2.170.246
HIU hydrolase0.219
Hydroxyisourate hydrolase0.001
HIU foldase0.000
Designed by MP, using an AMD MI250 GPU