MNMN0

Prompt

1.13.11.34

Oxidoreductases. Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. With incorporation of two atoms of oxygen. arachidonate 5-lipoxygenase.

AI Generated Sequence

242 AAs

MATYTVTVATGSDLFAGTDNYIHLTLVGQEGCSEKHLLDKPFYNDFERGAVDSYTVQCEEDLGKPILLKVERHKYWFDDDWYCKYITVKTPTVGDYVEFPCYRWITGREVVLREGRARTPQDDTIKILKQHRRQELETGRQRYRMSTWFKPGFPLIDIASLDDLPIDDMRFETKGIDFTLSIAALEAMNRGFMHLFQSWSRYDDLRKIFGVQKTNTLSEYVMHQWREDSFFGYQFLNGCNPM

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	73.0
NLMSIM	85.0
AACOMP	91.4
Seqdif (SeqID)	35.5 (XP_026655531.1)
Structdif (F-Target)	22.6 (4nre A)

ProtNLM

Name	Score
Arachidonate 5-lipoxygenase-like	0.200
Arachidonate 5-lipoxygenase	0.145
Arachidonate 5-lipoxygenase a	0.136
Arachidonate 5-lipoxygenase b, tandem duplicate 2	0.088
Arachidonate 5-lipoxygenase b, tandem duplicate 1	0.050
Arachidonate 5-lipoxygenase b, tandem duplicate 3	0.049