MNMEW

Prompt

6.3.2.26

Ligases. Forming carbon-nitrogen bonds. Acid--amino-acid ligases.(peptide synthases). N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase.

AI Generated Sequence

704 AAs

MTLLLAAWQALLYRYTGQEDVVVGTPVAGRNRPELEGLIGFFVNTLPLRVRLDGDPTFRELLGRVRQTALGAYAHQDLPFERLVEALQPERSLSHNPLFQVMFALQNTPLPLPGLTLEPLELDRGTAKFDLTLNVLETDGGLGGLFEYNTDLFDAATIARMAGHFQTLLEGVVAAPDTRVGELPLLTAAERQQLLAEWNGTAAAYPADRCVHQLFEAQAARTPDAVAVVCGEQRLTYAELNARANQLAHHLQALGVGPETLVGLCLERSLEMVVGLLGVLKAGGAYVPLDPAYPAERLAFMLEDAGAALLLTQAHLAARLPAAGARVLCLDAAWAAIAAAEPLPVAVAPDHLAYVIYTSGSTGRPKGVAIEHRSLVNFLVWMQERFGLGAGDRVLQFTSFSFDVSVWEIFGPLLNGACLVLAPEGVRDGAYLAALVREHRVTHLQFVPSLLQALVAEAAAAGLPALRLVLGGEALPAALAARWHALLPGARLWNAYGPTEATVWATAWECAGAAAAGAAPIGRPLANTQVYVLDAHLQPVPVGVAGELYIGGVGLARGYLNRPDLTAERFVPDPFGPAGARLYRTGDLARWLPDGALEFLGRVDHQVKVRGFRIELGEIEAALAAHPGVAQAVVVAREDAPGDKRLVAYVVAAGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Ligand/Cofactor

ATP

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N

Validation Metrics

PLDDT	90.1
NLMSIM	65.0
AACOMP	84.0
Seqdif (SeqID)	38.4 (MDR3670144.1)
Structdif (F-Target)	9.4 (6p1j B)

ProtNLM

Name	Score
Amino acid adenylation domain-containing protein	0.447
Non-ribosomal peptide synthetase	0.137
Carrier domain-containing protein	0.104
Amino acid adenylation domain protein	0.016
Nonribosomal peptide synthetase	0.012
Non-ribosomal peptide synthase domain TIGR01720/amino acid adenylation domain-containing protein	0.011