MNM2S

Prompt

1.6.3.2

Oxidoreductases. Acting on NADH or NADPH. With oxygen as acceptor. NAD(P)H oxidase (H2O-forming).

AI Generated Sequence

569 AAs

MGNWLVNEGLSRIFLVAWLGLNIFLFVYTFWIYDEEEKYFYTRHILGSALAWARAPAAVLNFNCMLILLPVCRNLISFLRGTSSCCSRRLRRQLDKNLTFHKMVAWMIAFNTAIHTIAHLFNVERYHNARVQNNGDLPAVLSSLGDKPNESYLNPIRTFRNGVTGGEVLFTRIAGITGVVITLALILIITSSTEFIRRSYFEVFWYTHHLFVIFFIGLAIHGAGRIVRGQTPESLRAHNPVYCRDHYADWGEIADCPIPQFSGNPMATWKWVIGPMMLYLCERLVRFWRSQQKVVITKVTTHFKTVLELQMKKKGFKMEVGQYIFVQCPSISKLEWHPFTLTSAPEEDYFSIHIRAIGDWTEGLFKAFGCEKQEFQEAWKLPKIAVDGPFGTASEDVFKYEVAMLVAAGIGVTPFASILKSIWYKYCNANSPLRLKKIYFYWICRDTHAFEWFADLLQLLEHQMQENGNADFLSYHIFLTGWDESQANHFAVHFDEEKDVITGLKQKTRFGRPNWDNEFKTIAQQHPSSRIGVFFCGPKALAKTLHKNCMSYSSDVPRGVHFIYNKEFS

Ligand/Cofactor

NADH

C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O

Validation Metrics

PLDDT	84.0
NLMSIM	75.0
AACOMP	93.7
Seqdif (SeqID)	22.0 (XP_019603449.1)
Structdif (F-Target)	13.8 (8gz3 B)

ProtNLM

Name	Score
NADPH oxidase 3	0.287
Cytochrome b-245 heavy chain	0.280
FAD-binding FR-type domain-containing protein	0.217
Cytochrome b-245 heavy chain-like	0.072
Cytochrome b-245 heavy chain-like protein	0.008
Superoxide-generating NADPH oxidase heavy chain subunit A	0.007