MNIS7

Prompt

1.8.1.8

Oxidoreductases. Acting on a sulfur group of donors. With NAD(+) or NADP(+) as acceptor. protein-disulfide reductase.

AI Generated Sequence

107 AAs
MTETIELTDAAFDAEVLKSALPVLVDFWAEWCGPCKMIAPILEEIAAEYAGKLKVAKLNIDANPATAAKYGVMAIPTLMLFKGGKEVARIVGALPKSAIAADIEKHL

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT94.0
NLMSIM99.5
AACOMP86.3
Seqdif (SeqID)34.6 (HEY63153.1)
Structdif (F-Target)1.3 (4ulx A)

ProtNLM

NameScore
Thioredoxin0.995
Thioredoxin 10.001
Thioredoxin domain-containing protein0.001
Thioredoxin C-10.000
Thiol reductase thioredoxin0.000
Thioredoxin-10.000
Designed by MP, using an AMD MI250 GPU