MNB95

Prompt

2.1.1.41

Transferases. Transferring one-carbon groups. Methyltransferases. sterol 24-C-methyltransferase.

AI Generated Sequence

436 AAs

MVAGLERDQDHRDDAEFKAKMHGESKQRGGTHSAMRSKGGAEKNAVDEYYKHWDNKPAKEETEEEIRARLDAYATVTHHYYNLATDLYEYGWGQSFHFCRCWPGESFPQAIARHEHYLAHQIGLKNGMRVLDVGCGVGGPAREIAKFTGANIVGLNNNDYQIERAEMYNKEYGLSNQQTFVKGDFMQMTFPDNSFDAVYAIEATVHAPKLEGVYSEIYRVLKPGGVFGVYEWLMDTDYDDNEPRHHRIRYGIERGDGIPSMCRTEEACDIALKCGGFLAFHEDLADTPDHPAWWYPLDGEVWYANTMNDFPTFVRMSKIGRWITHNCIGCLEKMGLAPGKSKRVTTALHVAAECLVEGGREKLFTPMYLMCARKPKPESASSGKAEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Ligand/Cofactor

S-adenosylmethionine

C[S+](CCC(C(=O)[O-])N)CC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O

Validation Metrics

PLDDT	83.6
NLMSIM	90.0
AACOMP	86.0
Seqdif (SeqID)	33.2 (XP_018701186.1)
Structdif (F-Target)	9.0 (6uv6 B)

ProtNLM

Name	Score
Sterol 24-C-methyltransferase	0.406
Delta(24)-sterol C-methyltransferase	0.330
2.1.1.41	0.198
SAM_MT_ERG6_SMT domain-containing protein	0.027
Sterol 24-C-methyltransferase erg-4	0.007
S-adenosyl-L-methionine-dependent methyltransferase	0.004