MN4AN

Prompt

1.14.99.15

Oxidoreductases. Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2. Miscellaneous. 4-methoxybenzoate monooxygenase (O-demethylating).

AI Generated Sequence

272 AAs
MRTQVAIIGAGPSGLLLGQLLHAAGIDNVILERKSRDYVLGRIRAGVLEEGTVDLLRDAGVSARMDAEGLPHDGCELAFGGRHYRIDLKALTGKTVTVYGQTEVTRDLWAEREAAGMPVLYAADNVPIHDFADSDPYVTYVRDGVTHRIDCDFIAGCDGFHGISRRSIPAASIKEFERVYPFGWLGILSETPPVSHELIYANHPRGFALCSMRSATRSRYYIQCSLDEKVENWSDERFWEELRKRLPDSVAELVTGPSIEKSIAPLRSFFVE

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT90.2
NLMSIM80.0
AACOMP94.2
Seqdif (SeqID)24.8 (WP_089796538.1)
Structdif (F-Target)2.4 (1bkw A)

ProtNLM

NameScore
1.14.13.20.537
4-hydroxybenzoate 3-monooxygenase0.390
P-hydroxybenzoate hydroxylase0.036
4-hydroxybenzoate hydroxylase0.017
P-hydroxybenzoate 3-monooxygenase0.007
FAD_binding_3 domain-containing protein0.001
Designed by MP, using an AMD MI250 GPU