MN07X

Prompt

1.13.12.8

Oxidoreductases. Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2. With incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases). Watasenia-luciferin 2-monooxygenase.

AI Generated Sequence

296 AAs
MKIGIFLPNTWLKGETITRPTMRKLHDLALKMAEELGFEYLWIGEHHELTRELCPDFMALAAYAGEFTKLRFGSTVVLTSFRHPAKLAKQAATLDHLSRGRLILGVGRGESQNEFDFMGYDWHKDRRRYTEEFLHIIKQVWTEEVVDYEGKFYRVENGLLVPKPQSDHPPIYFGATSEATLEVAGREADGYLMNFGESEEVKKQFDAMRAGAEAAGRVPFPIRLPQIARDDTEKARAAADELFKSMIDEKKAQWEAGMKEDSMGQEMLAQLEKLTEDGKEVTPEQIAGAVSLVLDA

Ligand/Cofactor

FAD

CC1=CC2=C(C=C1C)N(C3=NC(=O)NC(=O)C3=N2)CC(C(C(COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O)O

Validation Metrics

PLDDT81.0
NLMSIM75.0
AACOMP92.6
Seqdif (SeqID)66.1 (TET17301.1)
Structdif (F-Target)18.1 (1xkj B)

ProtNLM

NameScore
LLM class flavin-dependent oxidoreductase0.788
Bac_luciferase domain-containing protein0.068
Luciferase0.019
Luciferase family protein0.016
Luciferase-like monooxygenase0.014
LLM class F420-dependent oxidoreductase0.009
Designed by MP, using an AMD MI250 GPU