MMKPZ

Prompt

1.1.1.66

Oxidoreductases. Acting on the CH-OH group of donors. With NAD(+) or NADP(+) as acceptor. omega-hydroxydecanoate dehydrogenase.

AI Generated Sequence

500 AAs

MVYQGETLTVDLIDDGIAELRFGAPGSVNKLDRATVASLDAALAALEAHPDLKGLVVRSGKAAFIVGADITEFLDLFALPAEALIDWLRAVNAIFNSLEDLPVPTLAALRGHALGGGCEMVLATDYRLLAPEARIGLPETKLGIMPGFGGTVRLPRLIGADSALEIIAMGADVGAEAFLKDGAVDAVVAPESLLDAALAMLRQAIAGRLDWRARRQPRLEPLRLSPIEQAMSFTMAKGLVAQVAGKHYPAPMTAVKTIEAAAARPREDALALEAAGFVALARTPAQERLVGIFLNDQLVKGKARKLAKGVAPVEQAAVLGAGIMGGGIAYQSAWKGVPVMLKDIAPAALDLGMTEATKLLNKQRLRGRIDLGKMAGVLATIRPTLAAYFDRADVVVVEAVVENPKVKAAVLAETEALVPEGTVLASNTSTIPVDELAKGLKRPHFCGMHFFMPVHGRMPLVEIIRGEKTSEETIAKVAALATAMPTPGIVVNDCFGFFVN

Ligand/Cofactor

NAD(+)

C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N

Validation Metrics

PLDDT	86.9
NLMSIM	60.0
AACOMP	90.3
Seqdif (SeqID)	27.9 (SUX88111.1)
Structdif (F-Target)	7.6 (1wdk B)

ProtNLM

Name	Score
5.1.2.3	0.234
1.1.1.35	0.221
5.3.3.8	0.155
4.2.1.17	0.101
Enoyl-CoA hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA isomerase/3-hydroxybutyryl-CoA epimerase	0.074
3-hydroxyacyl-CoA dehydrogenase	0.072